tag:blogger.com,1999:blog-1812431336777691886.post819042840751908131..comments2024-02-29T03:57:00.088-05:00Comments on The Mermaid's Tale: The lessons of the Land: part IVAnne Buchananhttp://www.blogger.com/profile/09212151396672651221noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-1812431336777691886.post-53413572491443959412011-04-06T12:29:58.987-04:002011-04-06T12:29:58.987-04:00The idea is that if you have the whole genome (or ...The idea is that if you have the whole genome (or enough markers) then to the extent that there is genetic contribution, the DNA sequence must account for it all. How much of this can actually be found given measurement issues, statistical noise, and so on is a separate question. <br /><br />Likewise, since different samples will have different contributing sites, how much of what is found in a given sample that can be applied to additional samples is a different kind of question.<br /><br />And it should be easier in the much more controlled experimental setting.Ken Weisshttps://www.blogger.com/profile/02049713123559138421noreply@blogger.comtag:blogger.com,1999:blog-1812431336777691886.post-77342999850303481792011-04-06T11:47:15.994-04:002011-04-06T11:47:15.994-04:00Thanks. I'm reading some of the papers by Viss...Thanks. I'm reading some of the papers by Vissher et al.Javier G.noreply@blogger.comtag:blogger.com,1999:blog-1812431336777691886.post-91789888572938032432011-04-04T16:25:19.551-04:002011-04-04T16:25:19.551-04:00I don't remember if it was said, but with exha...I don't remember if it was said, but with exhaustive genome-spanning markers, the idea is that much if not all of the heritability can be accounted for by one marker scoring method or another. This will be easier in ag breeding because the population variation is restricted and experiments can be done.<br /><br />Generally, 'hidden' heritability is basically the result of many genetic contributions too small to be detected by the marker set used, the sample size, and so on.<br /><br />A good paper about the methods is Heffner et al., Crop Science 49:1-12, 2009. Papers by Peter Visscher, in the human context, and by Jannssens--that you can find by PubMed searching (my references are at work and I'm at home at the moment)--deal with these issues.Ken Weisshttps://www.blogger.com/profile/02049713123559138421noreply@blogger.comtag:blogger.com,1999:blog-1812431336777691886.post-34837602514541820552011-04-04T15:37:12.761-04:002011-04-04T15:37:12.761-04:00Where is the missing heritability? Is there in fac...Where is the missing heritability? Is there in fact missing heritability?Javier G.noreply@blogger.com