tag:blogger.com,1999:blog-1812431336777691886.post3366385808551685756..comments2024-02-29T03:57:00.088-05:00Comments on The Mermaid's Tale: Is telomere length a better predictor of longevity than astrology?Anne Buchananhttp://www.blogger.com/profile/09212151396672651221noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-1812431336777691886.post-65598933375989492392012-11-02T08:55:15.255-04:002012-11-02T08:55:15.255-04:00Dan Eisenberg has published some on this - first a...Dan Eisenberg has published some on this - first a review of overall biology here (http://tinyurl.com/a7wyehs) and had some data on early nutritional stress and infectious disease exposure at the last HBA meetings. I think some of the questions outlined above about different types of early life stress and telomere length (nutrition, growth, infection) should start to have information soon.EA Quinnhttps://www.blogger.com/profile/06213305158349164330noreply@blogger.comtag:blogger.com,1999:blog-1812431336777691886.post-89097223309571770382012-11-01T13:25:31.842-04:002012-11-01T13:25:31.842-04:00It's another example of one-size-fits-all clai...It's another example of one-size-fits-all claims to discovery and explanation. Such things--and they're to be found all over the place these days--typically elide the exceptions (and they're usually all over the place, too)!Ken Weisshttps://www.blogger.com/profile/02049713123559138421noreply@blogger.comtag:blogger.com,1999:blog-1812431336777691886.post-37362981500647062702012-11-01T12:14:07.875-04:002012-11-01T12:14:07.875-04:00I think much of the telomere story is a mess. For...I think much of the telomere story is a mess. For instance, how can telomerase negative cells maintain such long telomeres over hundreds of years and many cell divisions? Does it make a difference to shrink from 10kb to 6kb? Is this 4kb responsible for aging? (Chiang Y J et al. PNAS 2010;107:10148-10153) How about mice that grow normally for five generations with normal telomeres despite being telomerase negative. In cancer cells it is just as confusing...Telomerase is active but the telomeres are very short. Josh Nicholsonnoreply@blogger.com